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Understanding
Depression &

Understanding
Depression 

US Depression Rate.jpeg

Understanding Plant Medicine Therapy 

Depression

  • Study: "Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression"

    • National Library of Medicine - link to study: 

    • https://pubmed.ncbi.nlm.nih.gov/36378572/

    • Major Finding: A single dose of psilocybin produced rapid and significant antidepressant effects in patients with treatment-resistant depression.

Depression is more than just sadness; it’s a complex condition that affects mood, energy, cognition, and overall quality of life. Traditional treatments, such as SSRIs, can be effective but often come with side effects or limitations. That’s where plant medicine steps in, offering an alternative path to healing: 

  1. Promoting Neuroplasticity

  2. Reducing Negative Thought Loops

  3. Enhancing Emotional Processing

  4. Boosting Serotonin Receptors

​Research has shown that even a single guided plant medicine session can lead to significant, lasting reductions in depressive symptoms, making it a promising tool for those seeking a breakthrough in their healing journey.

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Mushroom & Cannabinoid Therapy

When used together in a mindful, intentional setting, mushrooms and cannabinoids can work synergistically to enhance healing. Compounds like psilocybin offers deep introspective and emotional breakthroughs, while CBG provides grounding and neuroprotective support, helping to integrate the experience into daily life.

At Nicayla Retreats, we create a safe, guided environment for individuals to explore these plant medicines with expert facilitators. Through carefully curated experiences, we help you:

  • Prepare for your journey with intention-setting and mindfulness practices

  • Experience deep emotional release and clarity

  • Integrate your insights into everyday life for lasting transformation

The Experience

Day 1 

Day 2

Day 3

Day 1: Grounding & Awakening

Theme: Connecting with Intention

  • Morning Welcome Breakfast & Opening Circle – Setting intentions, introductions, and breathwork.

  • Cannabis Meditation Ceremony – Guided meditation with cannabis to open awareness and promote deep relaxation.

  • Integrative Lunch – Mindful eating experience with nourishing, plant-based foods. Discussion on setting the foundation for transformation.

  • Kundalini Yoga & Breathwork – Awakening energy, clearing blockages, and preparing the mind-body for deeper healing.

  • Evening Reflection – Journaling, group discussion, and preparation for Day 2’s journey.

Day 2: Expansion & Healing

Theme: Journey Within

  • Morning Mindfulness Breakfast

  • Light Movement – Preparing the body and mind for the experience ahead.

  • Macro Mushroom Ceremony – A guided mushroom journey with facilitators, intention setting, and sacred space holding.

  • Sound Healing Journey – Deep vibrational healing through singing bowls, gongs, and other therapeutic sounds to integrate insights and enhance relaxation.

  • Integration & Rest – Gentle re-entry with supportive practices (tea, grounding foods, journaling).

  • Evening Reflection Dinner & Sharing Circle – Space for personal insights, emotional processing, and group connection.

Day 3: Integration & Beyond

Theme: Bringing the Experience Home

  • Morning Fairwell Breakfast

  • Morning Movement & Meditation – Gentle stretching, breathwork, and gratitude practice.

  • Mapping Your Healing Path – Workshop on integrating lessons, setting post-retreat intentions, and creating actionable plans for everyday life.

  • Closing Circle & Energy Alignment – Final reflections, community support, and commitment to continued growth.

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